Transparency data: Non-tech summaries 2016: projects on endocrine disorders

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This document outlines the projects granted under the Animals (Scientific Procedures) Act 1986 during 2016 with a primary purpose of translational applied research – human endocrine and metabolism disorders.

  • CNS regulation of energy homeostasis (obesity, inflammation, food-intake, body-weight, glia)

  • mitochondrial function in metabolic diseases (metabolism, heart, mitochondria, diabetes, obesity)

  • novel therapeutics for obesity and metabolic disorders (obesity, metabolic disorders, novel therapeutics)

  • the Rho-GTPase signalling network in health and disease (Rac-GEFs, small GTPases, signalling, inflammation, metabolism)

  • effects on metabolism and endocrine pharmacology (metabolism, endocrine, safety, efficacy, pharmacology)

  • understanding metabolic phenotypes in mouse lines (obesity, insulin, diabetes, mouse, genetics)

  • identifying diabetes, obesity and metabolic disease therapeutics

  • models for endocrine neoplasia (pituitary, parathyroid, pancreatic islets, MEN1, NETs)

  • metabolic dysfunction and degeneration (obesity, diabetes, vascular disease, alzheimer’s)

  • metabolism and toxicity in non-human primates (pharmaceutical, regulatory, primate)

  • cell therapy for diabetes (type 1 diabetes, regenerative medicine, islet transplantation, reprogramming, transdifferentiation)

  • mechanisms regulating obesity, growth and dementia (satiety, growth, alzheimer’s disease, dementia)

  • regulation of glucose homeostasis in vivo (diabetes, islets of Langerhans, insulin secretion, insulin action)

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